Book Review
Microarrays in Clinical Diagnostics
Book Review. Ed by T.O. Joos and P. Fortina
Pub. by Humana Press (2005), pp274, $135.00
Microarray technology is now well established in laboratories all over the world, both for rapid detection of genetic mutations and, increasingly, for simultaneously analysing the expression of a large number of proteins. In this book, a panel of academic and industrial investigators surveys the new world of microarray technology, describing in step-by-step detail diverse DNA and protein assays in clinical laboratories using state-of-the-art technologies. The advanced tools and methods described are designed for mRNA expression analysis, SNP analysis, identification and quantification of proteins, and for studies of protein-protein interactions.
Among the highlights are universal assays, antibody microarrays, direct labelling approaches and quality control techniques for protein microarray-based analysis. The protocols follow the successful ”Methods in Molecular Biology” series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and highly practical, Microarrays in Clinical Diagnostics combines a comprehensive collection of cutting-edge technologies with detailed laboratory methods to help clinical laboratory researchers design and perform microarray experiments for DNA and protein analysis, diagnostic testing and cancer research.
Because it is difficult to predict which particular technology will ultimately prevail, the editors have tried to assemble as comprehensive a survey as possible of the varied technologies currently in use and a large collection of detailed methods descriptions in order to support maximally scientists who design and perform microarray experiments.
Book Review
Humana Press Inc
