Early detection or rule out of MI
The new Elecsys high sensitive Troponin T assay, (TnT hs) from Roche is designed for use on cobas and Modular Analytics systems. The highly sensitive diagnostic assay has been developed to improve the detection or rule out of myocardial injury in early stages, and has excellent precision in the range of 0.003-10 ng/mL Troponin T in serum or plasma. While cardiac troponins have revolutionised the diagnosis of AMI, until recently assays were limited by a lack of sensitivity at the time of presentation and a lack of precision at the lower concentrations above the 99th percentile. The new assay is the only commercially available TnT assay and not only meets the stipulated precision requirements (<10% CV at the 99th percentile of the reference range) but also demonstrates the best level of assay designation (≥ 95% measurable normal values below the 99th percentile). In a recent comparative evaluation, the new test was shown to have the highest sensitivity (95%) and negative predictive value (99%) in the diagnosis of unstable angina at presentation.
Roche Diagnostic Systems
